Peripheral serotonin regulates postoperative intra-abdominal adhesion formation in mice
نویسندگان
چکیده
منابع مشابه
Effect of Emodin on Preventing Postoperative Intra-Abdominal Adhesion Formation
BACKGROUND Postoperative intra-abdominal adhesions are a major complication after abdominal surgery. Although various methods have been used to prevent and treat adhesions, the effects have not been satisfactory. Emodin, a naturally occurring anthraquinone derivative and an active ingredient in traditional Chinese herbs, exhibits a variety of pharmacological effects. In our study, we demonstrat...
متن کاملEffect of Hydrogen-Rich Saline on Postoperative Intra-Abdominal Adhesion Bands Formation in Mice
BACKGROUND Postsurgical peritoneal adhesions (PPAs) are pathologic fibrous bands within the peritoneal cavity. The aim of this study was to investigate the protective effect of hydrogen-rich saline (HRS) on PPAs formation in mice. MATERIAL AND METHODS Adhesions were induced in mice using the cecum rubbing model. The mice were allocated into 4 groups: control sham group without cecum rubbing; PPA...
متن کاملCordycepin prevents postoperative formation of intra-abdominal adhesion in a rat model: An experimental study.
BACKGROUND The aim of the present study was to investigate whether cordycepin prevented adhesion formation in a rat model. METHODS Rats were randomly assigned to 3 groups of 10 rats. CONTROL GROUP The absence of adhesion was confirmed via laparotomy. Adhesion group: The cecum was removed from the abdomen and scraped with a dry gauze bandage until petechial hemorrhagic foci developed. Cordyc...
متن کاملNf‐κb Decoy Oligodeoxynucleotide Decreases Postoperative Intra‐abdominal Adhesion
Methods Forty female BALB/c mice were randomly assigned into 2 groups. The mice were anesthetized and then midline abdominal incision was made. Peritoneal injury was given using cytobrush until deperitonealization. The experimental group (n = 20) received NF-κB decoy oligodeoxynucleotide (NF-κB decoy ODN) in the peritoneal cavity before abdominal closure, while the control group (n = 20) receiv...
متن کاملThe prevention of postoperative intra-abdominal adhesion formation with different methods: a review article
Intra-abdominal adhesions are almost inevitable after major abdominal surgery. Postoperative adhesions continue to be the major cause of small bowel obstruction and infertility. Peritoneal lesions caused by abrasion, ischemia, desiccation, infection, thermal injury and foreign bodies are the origin of adhesions. Fibrinous adhesions that develop within a few hours of operational trauma. This fib...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-10582-w